NURS 6521N – Pathophysiology of Osteoarthritis

NURS 6521N – Pathophysiology of Osteoarthritis

NURS 6521N – Pathophysiology of Osteoarthritis

Review Chapter 37 in the Huether and McCance text and Chapter 24 in the McPhee and Hammer text. Identify the pathophysiology of osteoarthritis and rheumatoid arthritis. Consider the similarities and differences of the disorders. Select two of the following patient factors: genetics, gender, ethnicity, age, or behavior. Reflect on how the factors you selected might impact the pathophysiology of the disorders, as well as the diagnosis of and treatment for the disorders.

Sample Solution

Osteoarthritis/ Rheumatoid Arthritis
Osteomyelitis and rheumatoid arthritis are two of the most common musculoskeletal conditions affecting individuals across the United States. Distinguished by cartilage degeneration and bony overgrowth, osteomyelitis affects approximately 13.9% of adults who are ?25 years of age.
Rheumatoid arthritis, unlike osteoarthritis, is an autoimmune condition characterized by inflammation, usually in bilateral joint, and systemic features, such as fatigue and fever (Dewing et al., 2012). Rheumatoid arthritis sufferers are typically younger than those who develop osteomyelitis, with rheumatoid arthritis occurring between 20 – 30 years of age, and the incidence peaking at 35 to 50 years of age (Dewing et al., 2012).

NURS 6521N – Pathophysiology of Osteoarthritis

Pathophysiology
Although the primary manifestations of osteomyelitis and rheumatoid arthritis involve the joints, the underlying pathophysiology of each condition is distinct. Normally, cartilage undergoes a remodeling process, stimulated by joint movement or use (Hinton et al., 2002). In osteomyelitis, this process is altered by a combination of mechanical, cellular, and biochemical processes, resulting in abnormal reparation of cartilage and an increase in cartilage degradation (Hinton et al., 2002).
Osteomyelitis is primarily characterized by progressive cartilage loss, accompanied by an increased thickness of the subchondral plate, osteophytes (new bone at joint margins) and subchondral bone cysts (Goldring et al., 2006).

…

Treatment

…

Conclusion

…

References

…

Kindly navigate to Order Now for a complete and more resourceful answer.