Long Acting injetables vs oral antipsychotics related to Evidence Based Practic and dissemination

Long Acting injetables vs oral antipsychotics related to Evidence Based Practic and dissemination

Long Acting injetables vs oral antipsychotics related to Evidence Based Practic and dissemination

Is a long acting injection a bettter source for compliance over oral medications in Schizophrenics?

The availability of long-acting risperidone injection may increase adherence and lead to improved clinical and economic outcomes for individuals with schizophrenia.

The objective of this study was to assess the cost effectiveness of long-acting risperidone, oral risperidone, olanzapine, quetiapine, ziprasidone, aripiprazole, and haloperidol depot in patients with schizophrenia over 1 year from a healthcare system perspective. Published medical literature, unpublished data from clinical trials and a consumer health database, and a clinical expert panel were utilized to populate a decision analytical model comparing the seven treatment alternatives.

The model captured rates of patient compliance, the rates, frequency and duration of relapse, incidence of adverse events, and healthcare resource utilization and associated cost (Edwards 2005). Sadly it comes down to money. Injections are expensive, yet make more sense. One injection or 30 pills, seems pretty clear. Long-acting injectable (LAI) antipsychotics are recommended for those people with a preference for this form of treatment and those who experience negative outcomes due to non-adherence with oral medication. LAI antipsychotics have been associated with improved outcomes and lower treatment discontinuation rates when compared with oral formulations.

Risperidone long-acting injection (RLAI) treatment is effective and well-tolerated in clinical trials. The aim of this study was to review RLAI prescribing practice and compare prescribing to best practice recommendations (Wheeler, a 2011). Evidence shows better outomes with long acting meds, pharmaeutical companies need to comply with price. Looking further into my search Possibly googling specific medications would have helped and possibly looking for specific out comes. (American Psychological Assoc.)

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References

Edwards, N. C., Locklear, J. C., Rupnow, M. F. T., & Diamond, R. J. (2005). Cost effectiveness of long-acting risperidone injection versus alternative antipsychotic agents in patients with schizophrenia in the USA. PharmacoEconomics, 23(Suppl 1), 75–89. https://doi-org.ezp.waldenulibrary.org/10.2165/00019053-200523001-00007

Wheeler, A., Vanderpyl, J., Carswell, C., Stojkovic, M., & Robinson, E. (2011). Explicit review of risperidone long-acting injection prescribing practice. Journal of Clinical Pharmacy & Therapeutics, 36(6), 651–663. https://doi-org.ezp.waldenulibrary.org/10.1111/j.1365-2710.2010.01219.x

The dissemination of EBP results serves multiple important roles. Sharing results makes the case for your decisions. It also adds to the body of knowledge, which creates opportunities for future practitioners. By presenting results, you also become an advocate for EBP, creating a culture within your organization or beyond that informs, educates, and promotes the effective use of EBP. Explain how you would disseminate the results of your project to an audience. Provide a rationale for why you selected this dissemination strategy.

EBP Dissemination:

The dissemination of EBP results serves multiple important roles. Sharing results makes the case for your decisions. It also adds to the body of knowledge, which creates opportunities for future practitioners. By presenting results, you also become an advocate for EBP, creating a culture within your organization or beyond that informs, educates, and promotes the effective use of EBP.

To Prepare:

• Review the final PowerPoint presentation you submitted in Module 5, and make any necessary changes based on the feedback you have received and on lessons you have learned throughout the course.
• Consider the best method of disseminating the results of your presentation to an audience.

To Complete:

Create a 5-minute, 5- to 6-slide narrated PowerPoint presentation of your Evidence-Based Project.

• Be sure to incorporate any feedback or changes from your presentation submission in Module 5.
• Explain how you would disseminate the results of your project to an audience. Provide a rationale for why you selected this dissemination strategy.