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Assignment 2: Evidence-Based Pharmacology Paper
The purpose of this assignment is to provide an opportunity for you to review an area of interest and apply the concepts you have learned in this course to a patient situation .In clinical decision making, you must combine knowledge and evidence to make a good decision .Using critical thinking and reading skills, you will meet multiple objectives for this assignment .
Criteria
Synthesize relevant information, including research related to the diagnosis and treatment of the selected disorder .
Recognize the assumptions inherent in the current literature and identify any unstated or missing information .
Develop and justify various approaches to the stated problem, including nonpharmacological and pharmacological treatment .
Clearly articulate at least two approaches to the treatment of the condition .
Defend the choice of the treatment option .This must include a reflection on the availability of peer-reviewed information and your analysis of the credibility of that information .
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Create a plan for follow-up and referral if needed .
The following are examples of disease states that you might want to study .These are just examples .You can select whatever area is of interest to you .
Asthma
Chronic Obstructive Pulmunory Disease (COPD)
Hypertension
Diabetes Mellitus Type II
Major Depression
Migraine Headaches
Pneumonia
Tuberculosis
Human Immunodeficiency Virus (HIV)
Hyperlipidemia
Submit your answers in a Microsoft Word document of 10–15 pages .Include peer-reviewed references in APA format .Be sure to review the directions and grading criteria to assure that you will cover the content well.
1 .Question :
The drug recommended as primary prevention of osteoporosis in men over seventy years is:
Alendronate (Fosamax)
Ibandronate (Boniva)
Calcium carbonate
Raloxifene (Evista)
Question 2 .Question :
Alterations in drug metabolism among Asians may lead to:
Slower metabolism of antidepressants, requiring lower doses
Faster metabolism of neuroleptics, requiring higher doses
Altered metabolism of omeprazole, requiring higher doses
Slower metabolism of alcohol, requiring higher doses
Question 3 .Question :
Some research supports that testosterone replacement therapy may be indicated in which of the following diagnoses in men?
Age-related decrease in cognitive functioning
Metabolic syndrome
Decreased muscle mass in aging men
All of the above
Question 4 .Question :
The chemicals that promote the spread of pain locally include _________ .
serotonin
norepinephrine
enkephalin
neurokinin A
Question 5 .Question :
The DEA:
Registers manufacturers and prescribes controlled substances
Regulates NP prescribing at the state level
Sanctions providers who prescribe drugs off-label
Provides prescribers with a number they can use for insurance billing
Question 6 .Question :
The trial period to determine effective anti-inflammatory activity when starting a patient on aspirin for RA is _____ .
forty-eight hours
four to six days
four weeks
two months
Question 7 .Question :
The route of excretion of a volatile drug will likely be:
The kidneys
The lungs
The bile and feces
The skin
Question 8 .Question :
Compelling indications for an ACE inhibitor as treatment for hypertension based on clinical trials include:
Pregnancy
Renal parenchymal disease
Stable angina
Dyslipidemia
Question 9 .Question :
The American Diabetic Association has recommended which of the following tests for ongoing management of diabetes?
Fasting blood glucose
Hemoglobin A1c
Thyroid function tests
Electrocardiograms
Question 10 .Question :
The angiotensin converting enzyme (ACE) inhibitor lisinopril is a known teratogen .Teratogens cause Type ____ ADR .
A
B
C
D
Question 11 .Question :
The goals of therapy when prescribing HRT include reducing:
Cardiovascular risk
Risk of stroke or other thromboembolic event
Breast cancer risk
Vasomotor symptoms
Question 12 .Question :
Patients who have angina, regardless of class, who are also diabetic should be on:
Nitrates
Beta blockers
ACE inhibitors
Calcium channel blockers
Question 13 .Question :
The New York Heart Association and the Canadian Cardiovascular Society have described grading criteria for levels of angina .Angina that occurs with unusually strenuous activity or on walking or climbing stair after meals is:
Class I
Class II
Class III
Class IV
Question 14 .Question :
Patients with allergic rhinitis may benefit from a prescription of:
Fluticasone (Flonase)
Cetirizine (Zyrtec)
OTC cromolyn nasal spray (Nasalcrom)
Any of the above
Question 15 .Question :
Kyle has Crohn’s disease and has a documented folate deficiency .Drug therapy for folate deficiency anemia is:
Oral folic acid 1 to 2 mg/day
Oral folic acid 1 gm/day
IM folate weekly for at least six months
Oral folic acid 400 mcg daily