NR 602 Week 2 -Periorbital Cellulitis Vaccine

NR 602 Week 2 -Periorbital Cellulitis Vaccine

NR 602 Week 2 -Periorbital Cellulitis Vaccine

Hello J,

Excellent presentation. Thank you for sharing wonderful information.

• What vaccine is given now to children that once was a cause of periorbital cellulitis?

The incidence of Haemophilus influenzae type B (HIB) infection, once the most common cause of periorbital cellulitis, declined dramatically after the introduction of HIB vaccine in 1990 (Sharma, et., al., 2015).

• What antibiotics would you give for orbital cellulitis?

All patients with orbital cellulitis should be admitted for empiric intravenous antibiotic therapy. Antibiotics should be covered sinus pathogens that exhibit beta-lactamose resistance and penetrate cerebrospinal fluid. All empiric antibiotic treatment should be targeted to the traditional pathogens: Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae (Cagan, Soysal, Bakir, 2015). The antibiotics for orbital cellulitis includes the following:

AB: Children >1 month of age: 40-100 mg/kg/day IV given in divided doses every 6-8 hours, maximum 6g/day.

CD: 20-40 mg/kg/day IV given in divided doses every 6-8 hours,

EF: Children ? 3 months of age : 50-150 mg/kg/day IV given in divided doses every 6-8 hours, maximum 6g/day.

GH: 30 mg/kg/day IV given in divided doses every 6 hours, maximum 4g/day.

If MRSA is suspected, then add Vancomycin: 40-60 mg/kg/day IV given in divided doses every 6-8 hours (Cagan, Soysal, Bakir, 2015) & (Lawrence & Schub, 2018).

NR 602 Week 2 -Periorbital Cellulitis Vaccine

** If MRSA is suspected, or there is concern for antibiotic resistance, treat with Vancomycin plus cefotaxime and clindamycin, or alternatively, vancomycin plus piperacillin/tazobactam. Daptomycin, linezolid, and telavancin are potential alternatives for patients who are allergic to vancomycin (Kingsley, Mehra, & Lawrence, et, al., 2016)

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3A) Periorbital cellulitis is also known as what? 3B)Orbital cellulitis is also known as what?

Preorbital cellulitis is also known as Preseptal cellulitis and Orbital cellulitis is also known as Postseptal cellulitis (Lawrence & Schub, 2018).

NR 602 Week 2 -Periorbital Cellulitis Vaccine

Reference :

Eren Cagan, Ahmet Soysal, & Mustafa Bakir. (2015). Evaluation of Pediatric Patients with Orbital and Preseptal Cellulitis. Çukurova Üniversitesi T?p Fakültesi Dergisi, Vol 40, Iss 2, Pp 267-274 (2015), (2), 267. Retrieved from https://chamberlainuniversity.idm.oclc.org/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=edsdoj&AN=edsdoj.fca12e8ceac04aa183801db73d3ebbb0&site=eds-live&scope=site

 

Lawrence, P. R. M. B. B. C., & Schub, T. B. (2018). Cellulitis: Preseptal and Orbital. CINAHL Nursing Guide. Retrieved from https://chamberlainuniversity.idm.oclc.org/login?url=https://search.ebscohost.com/login.aspx?direct=true&db=nup&AN=T702456&site=eds-live&scope=site

Kingsley, J., Mehra, P., Lawrence, L. E., Henry, E., Duffy, E., Cammarata, S. K., & Pullman, J. (2016, March). A randomized, double-blind, Phase 2 study to evaluate subjective and objective outcomes in patients with acute bacterial skin and skin structure infections treated with delafloxacin, linezolid or vancomycin. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/26679243

Sharma, A., Liu, E. S., Le, T. D., Adatia, F. A., Buncic, J. R., Blaser, S., & Richardson, S. (2015). Pediatric orbital cellulitis in the Haemophilus influenzae vaccine era. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/25900771