NR 507 Discussion – Pathophysiology Cases

NR 507 WK 1 Discussion- Pathophysiology Cases

NR 507 WK 1 Discussion- Pathophysiology Cases

NR 507 Week 1 Discussion:
PART 1:

John is a 19-year-old college football player who presents with sneezing, itchy eyes, and nasal congestion that worsens at night. He states that he has a history of asthma, eczema and allergies to pollen. There is also one other person on the football team that has similar symptoms. His vitals are BP 110/70, P 84, R 18, T 100 F.

Write a differential of at least three (3) possible items from the most likely to less likely. For each disease include information about the epidemiology, pathophysiology and briefly argue why this disease fits the presentation and why it might not fit the presentation.

NR 507 WK 1 Discussion- Pathophysiology Cases

PART 2:

A patient has been admitted into the emergency room that was in the passenger side of a car that collided with another car head on. The patient is pale, barely conscious and has a weak and thready pulse. An IV is started. The vitals are BP 80/50, P 140, T 96.0 and R 26. As the team fights to keep the patient alive they have to remove the spleen. Blood is given but it has been mistyped. A transfusion reaction occurs.

Describe the type of hypersensitivity reaction that has occurred and discuss the molecular pathophysiology of the specific type of hypersensitive reaction you have chosen.

In the event that this patient survived the car accident and the transfusion reaction which organs are most likely to be damaged and why?

NR 507 WK 1 Discussion- Pathophysiology Cases

PART 3:

A 44-year-old patient presents with lump in the chest of approximately 2 cm in diameter. There is a slight dimple over the location of the lump and when the lump is manipulated it seems to be attached to the surrounding tissue. A lumpectomy is performed and the mass is sent to pathology. The pathology report comes back and the mass is confirmed to be an estrogen receptor negative, a progesterone receptor negative and a her2/neu receptor positive breast cancer.

• What are some of the risk factors for breast cancer?

• What tumor suppressor genes are associated with breast cancer?

• What tumor oncogenes are associated with breast cancer?

• Compare and contrast tumor suppressor genes from oncogenes?

NR 507 WK 1 Discussion- Pathophysiology Cases